Post #4 XCell-Center Treatment on Feb 4, 2010

At this time we would like to continue sharing our research and experiences related to stem cell treatments with you. This post will describe Mariko's recent stem cell treatment, while the next one will focus on our research regarding stem cell treatments in general, as well as more specific information and impressions regarding XCell-Center in Germany.

Mariko received a stem cell treatment at XCell-Center in Germany on February 4th. Bone marrow was collected on February 2nd, after which the stem cells were isolated from the bone marrow and subsequently implanted on February 4th into the cerebro-spinal fluid by lumbar puncture. Over 4 million stem cells were harvested with a vitality in excess of 90 per cent. The theory is that since the cerebro-spinal fluid circulates, the implanted stem cells are transported directly to the damaged tissue in the brain.

The procedure went well, without incident. However, there were some unexpected side-effects. Although the headache was avoided that sometimes, reportedly, accompanies the treatment, she did experience severe discomfort (severe enough to be considered pain) in the legs and buttocks for 2-3 days. And although the leg discomfort subsided after about the 3rd day, there is still some discomfort in the area of the buttocks (especially when she bends over), almost one week after treatment.

Reportedly, the beneficial effects of the treatment will likely not be felt until sometime during the 2nd or 3rd month following the stem cell implantation. We both remain hopeful there will be noticeable benefits, even though we recognize this is not a cure for the disease, and as such any continuing benefits will be limited due to the degenerative nature of the disease.

It is our objective to post results here as accurately as possible (we recognize that some of our measurement criteria will be somewhat subjective in nature) and on a periodic, somewhat regular basis (at least every 2-4 weeks). If anyone has specific questions for us, we have posted our e-mail address, and we will respond in as timely a manner as possible.